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36006 Screen Quest Membrane Potential Assay Kit Red Fluo

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Screen Quest检测试剂盒是一类用于检测各种细胞离子通道以及电位等系列工具,包括膜电位、钙离子流、多药物抗性、氯离子以及氯离子通道等方面的指标。每种检测方案均能提供不同的检测方案。

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 产品描述:

       Screen Quest检测试剂盒是一类用于检测各种细胞离子通道以及电位等系列工具,包括膜电位、钙离子流、多药物抗性、氯离子以及氯离子通道等方面的指标。每种检测方案均能提供不同的检测方案。这些高效的检测方案为从多角度研究细胞功能活动提供了一种十分有效的方法。细胞膜内外具有不同的膜电压。膜电位使得细胞具有类似电池的功能,提供电源操作镶嵌在膜上多种小分子装置。在可电刺激激的细胞中,例如神经元,膜电位常用于细胞不同的区域信号传递。细胞膜上某处离子通道的开或者关,会诱导产生局部膜电位改变,并引起电流快速传到膜上的另一处。离子通道已经被鉴定为重要药物发现的目标。

 

产品特性:

      Screen Quest膜电位检测试剂盒 *红色荧光* 提供了一种快速且均匀检测方案,它使用我们*的长波长膜电位指示器来检测由于离子通道开放或者关闭而形成的膜电势改变。我们试剂盒使用红色荧光的膜电位指示器在进入细胞后荧光强度增强,并降低来自于筛选复合物或者细胞自体荧光的干扰。

 

产品性能:

     Ex 635um    

 Em660um   

 

产品英文注释:

       Membrane potential is the difference in voltage between the interior and exterior of a cell. The membrane potential allows a cell to function as a battery, providing power to operate a variety of molecular devices embedded in the membrane. In electrically excitable cells such as neurons, membrane potential is used for transmitting signals between different parts of a cell. Opening or closing of ion channels at one point in the membrane produces a local change in the membrane potential, which causes electric current to flow rapidly to other points in the membrane. Ion channels have been identified as important drug discovery targets. Our Screen Quest Membrane Potential Assay Kit is a homogeneous assay with fast read time. It uses our proprietary long wavelength membrane potential indicator to detect the membrane potential change that is caused by the opening and closing of the ion channels. The red fluorescence of the membrane potential indicator used in the kit has enhanced fluorescence upon entering cells and minimizes the interferences resulted from the screening compounds and/or cellular autofluorescence.

 

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