动物行为轨迹分析平台

6. 黑白箱实验（light dark box）

  The subject is placed in the dark portion of the box for a set period of acclimation time.  At the end of this period, a door separating the two compartments is opened.  The amount of time that the subject takes to emerge fully from the enclosed area into the open area is measured.

7. 社交行为实验（social interaction）

  The subject is habituated to the test chamber and allowed to freely explore for a set time.   A novel animal is placed in one of the two enclosures, and the percentage of time the mouse spends in the section with the novel animal is compared to the time spent in the section with the empty enclosure.   In a later session, the time spent with the same animal might be compared to time spent with a newer, more novel animal.

8. 条件性位置偏爱（Conditioned Place Preference）

   条件性位置偏爱实验（Conditioned Place Preference, CPP）实验是目前评价药物精神依赖性的经典实验模型，也是广泛应用于寻找抗觅药行为的有效工具。该实验将实验动物（大鼠、小鼠）置于条件性位置偏爱箱的白色观察区，并给予精神依赖性药物（例如*），然后观察实验动物在条件性位置偏爱箱的黑色区和白色区的活动情况，白色区、黑色区以及其中的灰色 区之间有小门可供动物自由穿梭。动物每次处于给药区就会在药物奖赏性效应的作用下对黑色和白色区域产生位置上的偏好，其程度与药物的精神依赖性相关。

9.   悬尾

悬尾实验主要用于抗抑郁、镇静以及止痛类药物的研究。悬尾实验系统适用于大鼠、小鼠或其他实验室动物，通过固定动物尾部使其头向下悬挂，记录处于该环境的动物产生绝望的不动状态过程中的一系列参数。

10. 条件性恐惧实验（fear conditioning）

条件性恐惧分析用于小型啮齿类动物（大、小鼠）环境相关条件性恐惧实验研究。抗抑郁药和抗中枢兴奋药可以明显缩短不动状态持续的时间。实验过程中，实验对象被给与一个声音信号，随后给予电击刺激。该训练称为条件性训练，训练结束后实验动物进行声音信号或环境性实验。一般情况下啮齿类动物对相应的环境和不同环境下同样的声音信号都会做出明显的条件性恐惧反应，如静止不动。

11. 震惊条件反射（startle and pre-pulse inhibition）

      12．新颖物体识别（novel object recognition）

      The subject is habituated to the test chamber and allowed to freely explore for a set time.   A novel object is placed in one of the two enclosures, and the percentage of time the mouse spends in the section with the new object is compared to the time spent in the section with the empty enclosure.   In a later session, the time spent with the same object might be compared to time spent with a newer, more novel object.