稳定冻干蛋白配方的合理设计方面的实用建议 Rational Design of Stable Lyophilized Protein Formulations

Why use lyophilization to prepare stable protein drug products?

Early in the development of a protein therapeutic it is essential to design a formulatian that is stable during shipping and long-term storage. Obviously,an aqueous liquid formulation is the easiest and most economical to handle during manufacturing,and is the most convenient for the end user. 

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